A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
Antibody-drug conjugates (ADCs) are composed of monoclonal antibodies targeting specific antigens and small-molecule cytotoxic drugs linked by linkers, which have both the powerful killing effect of traditional small-molecule chemotherapy and the tumor targeting of antibody drugs. Up to date, 14 antibody-drug…