Zoe Zoe

Introduction Liposomes as carriers of antibacterial drugs can significantly improve the distribution of antibacterial drugs in tissues and enhance the release of drugs at the target site, thus enhancing the antibacterial effect and reducing adverse reactions. And it can also overcome…

Introduction to DiabetesDiabetes mellitus is a metabolic disease caused by multiple etiologies and characterized by chronic hyperglycemia. Abnormal metabolism of carbohydrates, fats, proteins, water and electrolytes due to defects in insulin secretion and/or action (insulin resistance). Types of DiabetesDiabetes can…

Hydrocarbon activation has become a powerful tool in molecular science research and great progress has been made in molecular science research in recent years. In particular, weak O-coordinated carboxylic acid-assisted oxidative C-H cyclization was achieved by continuous breaking of C-H…

Modern healthcare would not be possible without the usage of many polymer-based medical products. Many things we take for granted such as exam gloves, syringes, intravenous (IV) blood bags and even most artificial organs, etc. are all made of polymers.…

siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation (Fig. 1). The mRNA is targeted for cleavage through the catalysis of the RISC protein Ago2,…

Targeted therapies have significantly advanced the field of cancer therapy, and among these, antibody-drug conjugates (ADCs) have emerged as a viable therapeutic strategy. ADCs increase efficacy and decrease systemic toxicity by fusing the potency of cytotoxic drugs with the specificity…

IntroductionFlavors are generally divided into natural flavors and artificial flavors, of which natural flavors are widely used, but natural flavors have low bioavailability, poor absorption, rapid metabolism, poor stability, easy oxidation, irritability, and other problems. In general, such problems can…

Assessing the absorption, distribution, metabolism, and excretion (ADME) of lead compounds during drug discovery and development is an essential component of drug preclinical development. The In vitro ADME studies provide key physicochemical and pharmacological properties that drive the safety and efficacy of…

Prediction of ADMET (absorption, distribution, metabolism, excretion, and toxicity) is an essential step in drug design and drug screening. The ADME absorption distribution metabolism and excretion is considered a chemical compound within an organism. ADME/Tox prediction has been applied to investigate the…