Alzheimer’s disease (AD) is a progressive neurodegenerative disease with an insidious onset. Clinically, it is characterized by comprehensive dementia manifestations such as memory impairment, aphasia, apraxia, agnosia, impairment of visuospatial skills, executive dysfunction, and personality and behavioral changes. Alzheimer’s disease ...
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On: March 21, 2024
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What is Herpes Simplex Virus
Herpes simplex virus (HSV) belongs to the herpesvirus alpha subfamily and has a unique 4-layer structure. The core of HSV is a linear double-stranded DNA of about 152 000 bp, surrounded by an icosahedral capsid. The outer capsid is a ...
On: February 25, 2024
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The Role of Targeting p53 Signaling Pathway in Cancer Therapy
As a tumor suppressor, p53 is one of the most commonly mutated genes in human cancers. Due to its important role in tumor suppression, p53 has attracted great interest from researchers in drug development. As a transcription factor, p53 is directly or ...
On: February 25, 2024
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The Role of CXCR5/CXCL13 Axis in Tumors
The tumor microenvironment is composed of tumor cells and non-tumor cells (including fibroblasts, vascular and lymphatic endothelial cells, various immune cells) and extracellular components (such as extracellular matrix, cytokines, inflammatory factors, chemokines, etc.) in tumor tissues. Factors, etc.) interact to form ...
On: January 16, 2024
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Gametes and Fertilization
Gametes and fertilization overview Sexual reproduction refers to the sexual germ cells (gametes) produced by the parents, through the combination of bisexual germ cells (such as sperm and egg cells), become the fertilized egg, and then the fertilized egg develops ...
On: January 16, 2024
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Oxytocin Signaling Pathway
Oxytocin overview The oxytocin signaling pathway refers to signaling pathway proteins including oxytocin, oxytocin receptors, and related regulatory factors. Oxytocin is a peptide hormone secreted by the posterior pituitary. Synthesized from the hypothalamic paraventricular nucleus and supraoptic nucleus, it consists ...
