Introduction

Feeling tired and down? B12 injections promise to give you an energy boost and lift your spirits. But do they really work? Here’s what you need to know about B12 injections for low energy and mood.

What is Vitamin B12?

Vitamin B12 is an essential nutrient that helps keep the body’s nerve and blood cells healthy. It also plays a role in producing DNA. Vitamin B12 is naturally found in foods like meat, fish, eggs and dairy.

The daily recommended amount of B12 is 2.4mcg. B12 deficiency can cause fatigue, weakness, constipation, loss of appetite, weight loss, neurological problems, and psychiatric issues like depression.

What are B12 Injections?

B12 injections are shots that contain high doses of vitamin B12. They are administered into the muscle or under the skin.

Some people get B12 injections from their doctor if they have a deficiency. Others use them to correct a perceived energy or mood imbalance, even if they don’t have a true B12 deficiency.

Can B12 Injections Boost Energy and Mood?

For those with a clinically diagnosed B12 deficiency, B12 injections can correct the deficiency and resolve symptoms like fatigue and depression.

But there is no good evidence that B12 injections provide an energy or mood boost in those without a true B12 deficiency.

A placebo effect is more likely – some people may feel more energetic after getting a B12 injection simply because they expect to. Any mood lifting effects are also likely psychological rather than physiological.

Other Effects of B12 Injections

While B12 injections may not physically increase energy or improve mood, some users report other benefits like:

Healthier skin, hair and nails
Enhanced brain function
Improved sleep
Boosted metabolism
Increased immunity

However, these effects are anecdotal and not confirmed by scientific research.

Are B12 Injections Safe?

B12 injections are generally considered safe, even in higher doses. Unlike oral supplements, there is very little risk of toxicity or overdose.

Side effects are usually mild and may include:

Redness, pain or itching at the injection site
Headache
Nausea
Dizziness
Anxiety

More serious side effects are possible in those with underlying health conditions. It’s important to speak with your doctor before getting B12 injections.

Who Should Be Cautious With B12 Injections?

The following people should use caution with B12 injections:

Those with an allergy to cobalt or any ingredients in the B12 injection
People with leukemia or other cancers
Those with gout or kidney dysfunction
People taking the diabetes medication metformin
Those with iron deficiency
Anyone with a suspected B12 deficiency (blood testing should be done first)

Women who are pregnant or breastfeeding should also speak to their doctor before getting B12 injections.

How Often Should You Get B12 Injections?

There is no standardized schedule for B12 injections. Those with a deficiency may get them 1-2 times per week at first, then once a month for maintenance.

For energy, mood or general health, most providers recommend B12 injections 1-2 times per month. It’s best to start slowly and see how your body responds.

Don’t get injections more frequently than recommended without medical supervision. Taking too much B12 can mask a serious underlying condition.

The Bottom Line

While vitamin B injections are safe for most people, they aren’t a magic bullet. There is little evidence they increase energy or mood in those without a true B12 deficiency.

Talk to your doctor to find out if B12 injections are right for you. Make sure you address any underlying health or lifestyle issues that may really be causing fatigue or depression.

Proper diet, exercise, stress management and social support are still your best tools for staying energized and emotionally healthy.

FAQs

What are the benefits of B12 injections?

For those with a B12 deficiency, injections can correct the deficiency and improve symptoms. However, there is little proof of benefits like increased energy, better mood, enhanced brain function or immunity in those without a deficiency.

How much does a B12 injection cost?

The cost for B12 injections ranges from $10-$50 per injection. Most providers recommend getting injections 1-2 times per month. Some health insurance plans may cover B12 injections if you have a verified deficiency.

What is the best method for B12 injections?

B12 injections are either intramuscular (into the muscle) or subcutaneous (under the skin). Intramuscular injections may be better absorbed but are more painful. Subcutaneous injections into the fat layer of the skin are easier and less painful but absorption may not be as robust.